Leif Svensson.

Of the 1276 individuals, 620 were randomly assigned to get compression-only CPR, and 656 patients to get standard CPR; 1036 patients were treated per protocol, and 149 didn’t have the assigned treatment. A complete of 113 of the 901 sufferers assigned to receive compression-only CPR were instead given standard CPR because the dispatchers incorrectly provided standard-CPR instructions. The two treatment groups were related with regards to the baseline features of the patients and the episodes of cardiac arrest . Primary and Secondary Outcomes The primary analysis showed a 30-day survival rate of 8.7 percent in the group receiving compression-only CPR and 7.0 percent in the group receiving standard CPR .

Martin, M.D., Janet E. Hall, M.D., and Nelly Pitteloud, M.D.: A Genetic Basis for Functional Hypothalamic Amenorrhea Reproduction can be an energetically costly procedure for women, and body’s defence mechanism have evolved that temporarily inhibit reproduction under adverse conditions.5 This frequent reason behind female infertility is diagnosed as functional hypothalamic amenorrhea, defined as the absence of menses, low or normal gonadotropin levels, and hypoestrogenemia without organic abnormality.7 The exquisite sensitivity of the GnRH pulse generator to energy deficits is evidenced by the actual fact that serum degrees of leptin, a signal of fat reserves, are often low in individuals with hypothalamic amenorrhea and that leptin substitute can restore GnRH pulsatility.8-10 Following the underlying stressors have been eliminated, normal reproductive function resumes in most cases.12,13 However, it is unknown whether this susceptibility reflects a genetic predisposition to hypothalamic amenorrhea.Martin, M.D., Janet E. Hall, M.D., and Nelly Pitteloud, M.D.: A Genetic Basis for Functional Hypothalamic Amenorrhea Reproduction can be an energetically costly procedure for women, and body’s defence mechanism have evolved that temporarily inhibit reproduction under adverse conditions.5 This frequent reason behind female infertility is diagnosed as functional hypothalamic amenorrhea, defined as the absence of menses, low or normal gonadotropin levels, and hypoestrogenemia without organic abnormality.7 The exquisite sensitivity of the GnRH pulse generator to energy deficits is evidenced by the actual fact that serum degrees of leptin, a signal of fat reserves, are often low in individuals with hypothalamic amenorrhea and that leptin substitute can restore GnRH pulsatility.8-10 Following the underlying stressors have been eliminated, normal reproductive function resumes in most cases.12,13 However, it is unknown whether this susceptibility reflects a genetic predisposition to hypothalamic amenorrhea.