Somewhat surprisingly, PCR analysis revealed that the primary laryngeal tumor lacked the mutant viral genome. To verify that the laryngeal site lacked this mutant genome, we utilized RCA to amplify and sequence the viral genome from the larynx. The produced HPV-11 genome acquired the prototype size of 7933 bp, a discovering that suggests that duplication had happened during tumor extension into the lung. The HPV genomes present in the larynx and lung, furthermore to differing in genome size, contained several mutations throughout the genome that differ from the prototype HPV-11 sequence .The current presence of bubbles of any size in tubes used to convey liquids into the blood supply can be highly damaging. Nevertheless, in other noncritical fluid handling applications, bubbles of a certain size might not affect the procedure of the operational system. In medical applications, the tube diameter isn’t restricted, however the technology is available off the shelf for 2-7mm tubes currently. However, in a few applications, really small bubbles do not present a danger and you don’t have for flow to end up being interrupted. As well as detecting bubbles ranging from a few microlitres to several millimetres in proportions, our sensors are able to fulfil the necessity of detecting foam as air.