4SC commences treatment in its resminostat Phase II trial for HL 4SC AG sulbutiamine.review.

4SC commences treatment in its resminostat Phase II trial for HL 4SC AG , a medication discovery and development company focused on autoimmune and cancer indications, today announced the treating the first patient in a Stage II study evaluating resminostat , an oral pan-histone-deacetylase inhibitor in relapsed or refractory Hodgkin’s Lymphoma patients. In this open-label, single-arm, Simon-design two-stage Phase II study entitled ‘SAPHIRE’, resminostat will get orally at a dosage of 600mg daily for five consecutive days, followed by a nine day time treatment free period . In the main stage of the trial, individuals will receive treatment for six cycles sulbutiamine.review .

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